HMB

An individual would need to consume over 600 g of high quality protein to obtain the amount of leucine (60 grams) necessary to produce the typical 3 g daily dosage of HMB used in human studies [ R ] .

The primary utility of HMB in the body is to inhibit the catabolism of muscle tissue [ R ].

HMB is an isolated metabolite of the protein synthesis-activating essential amino acid leucine [ R ].

Upregulates Anabolic Signaling* (Increase Muscle Protein Synthesis) [ R, R, R ].

Reduces DOMS* (Delayed Onset Muscle Soreness) [ R , R ].

For the purpose of muscle protein synthesis, HMB and leucine are fairly equivalent, but in the context of attenuating muscle loss, that’s where HMB appears to shine in its application [ R ] .

Potent Anti-Catabolic* (Reduce Muscle Breakdown) [ R, R, R ].

HOW DOES IT WORK?

Literature suggests that HMB may attenuate muscle loss and exercise-induced muscle damage (e.g.

This can include bodybuilding prep, low protein diets, general caloric restriction, high-intensity training, aging, high stress, fasting, periods of bed rest, illness, injuries, etc.

HMB excels during times when the risk of muscle catabolism is elevated [ R ] .

1-3 grams of HMB is seen as equivalent to 20–60g of leucine supplementation for this purpose [ R, R ].

This doesn’t mean throw your EAA’s in the garbage and start pounding HMB, they each may have their own individual use case.

Upregulates Anabolic Signaling* (Increase Muscle Protein Synthesis) [ R , R , R ].

Enhances Recovery* [ R ].

This can include bodybuilding prep, low protein diets, general caloric restriction, high-intensity training, aging, high stress, fasting, periods of bed rest, illness, injuries, etc. [ R ].

An individual would need to consume over 600 g of protein to obtain the amount of leucine (60 grams) necessary to produce the typical 3 g daily dosage of HMB used in human studies [ R ].

Size

120 Servings

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